SNCA Protein (E46K)
Aperçu rapide pour SNCA Protein (E46K) (ABIN7316762)
Antigène
Voir toutes SNCA ProtéinesType de proteíne
Origine
Source
Pureté
Classe de qualité
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Attributs du protein
- E46K
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Fonction
- Human Alpha-Synuclein (E46K) Protein, Tag Free (MALS verified)
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Séquence
- Met 1 - Ala 140
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Attributs du produit
- Human Alpha-Synuclein (E46K), Tag Free is expressed from E.coli cells. It contains AA Met 1 - Ala 140 (Accession # P37840-1 (E46K).
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niveau d'endotoxine
- 1.0 EU per μg
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Synuclein, alpha (SNCA) (A53T) (Active) protein
SNCA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) proteinSNCA Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (His-IF2DI Tag)SNCA Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (active) proteinSNCA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
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Commentaires
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This protein carries no "tag". The protein has a calculated MW of 14.5 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 50 mM HEPES, 100 mM NaCl, pH 8.0
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Stock
- -80 °C
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Stockage commentaire
- -70°C
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- SNCA (Synuclein, alpha (SNCA))
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Autre désignation
- Alpha-Synuclein
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Sujet
- Synonyms:N/A,Description:Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
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Poids moléculaire
- 14.5 kDa
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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